US Residents Only


Zokinvy® capsules are taken twice a day with meals, with flexible options to fit your family member’s needs


Zokinvy is available in 50-mg and 75-mg capsules to provide administration options for starting dosage and maintenance dosing.


The contents of Zokinvy can be mixed with Ora-Blend SF® or Ora-Plus®.

  • If your family member cannot access or tolerate Ora-Blend SF or Ora-Plus, you can mix the contents of Zokinvy capsules with orange juice or applesauce.

  • Do not mix Zokinvy with any juice containing grapefruit or Seville oranges.

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Do not take ZOKINVY if you are taking:

  • a strong or moderate CYP3A inhibitor or inducer
  • midazolam
  • lovastatin, simvastatin, and atorvastatin

WHAT IS Zokinvy® (lonafarnib)?

ZOKINVY (zoh-KIN-vee) is a prescription medicine used to treat Hutchinson-Gilford Progeria Syndrome and some types of Progeroid Laminopathies known as processing-deficient Progeroid Laminopathies. These illnesses are caused when the body makes harmful proteins called progerin and progerin-like proteins.